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ADORA2A (Y361) polyclonal antibody

货号: BS2706

价格：￥ 660

货期：现货（1-2个工作日）

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No. :BS2706

Product Name :ADORA2A (Y361) polyclonal antibody

Swiss-Prot :P29274

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :IHC IF

Application_all :IHC: 1:50~1:200 IF: 1:50~1:200

Background :Adenosine is involved in a variety of processes, including the synthesis of urea, the anti-inflammatory response and the inhibition of protein synthesis. The adenosine receptors, including Adenosine A1-R, Adenosine A2A-R, Adenosine A2B-R and Adenosine A3-R, are integral membrane proteins that are members of the G protein-coupled receptor family. The A1-R protein mediates ureagenesis in a partially calcium-dependent manner. Adenosine is known to mediate coronary vasodilation via the A2A-R receptor. Collagen synthasis and total protein synthesis are inhibited in certain cells by adenosine, acting via the A2B receptors. Activation of the A3-R receptor inhibits the induction of the cytokine TNFα and blocks the endotoxin CD14 receptor signal transduction pathway.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :ADORA2A (Y361) polyclonal antibody detects endogenous levels of Adenosine receptor A2a protein.

BiowMW :~ 45 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Adenosine receptor A2a; ADORA2; Adenosine A2A-R

Immunogen :Synthetic peptide, corresponding to amino acids 330-380 of Human ADORA2A.

Conjugate :Unconjugated

Modification :Unmodification

Immunohistochemistry (IHC) analyzes of ADORA2A (Y361) pAb in paraffin-embedded human colon carcinoma tissue at 1:50.showing Cell membrane and Cytoplasm staining. Negative control (the right)Using PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG-biotin followed by avidin-peroxidase.

Immunohistochemistry (IHC) analyzes of ADORA2A (Y361) pAb in paraffin-embedded human lung carcinoma tissue at 1:50.showing Cell membrane and Cytoplasm staining. Negative control (the right) Using PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG-biotin followed by avidin-peroxidase.