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XRCC1 monoclonal antibody

货号: MB23249

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB23249

Product Name :XRCC1 monoclonal antibody

Swiss-Prot :P18887

Host :Mouse

Reactivity :Human, Monkey

Applications :WB,IHC,FCM

Application_all :WB:1/500 - 1/2000 IHC:1/200 - 1/1000 FC:1/200 - 1/400

Background :The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.</p>

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :69.5kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :RCC; SCAR26

Immunogen :Purified recombinant fragment of human XRCC1 (AA:1-150) expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using XRCC1 mouse mAb against Hela (1), Jurkat (2),k562 (3),SK-OV-3 (4), and COS-7 (5) cell lysate.

Immunohistochemical analysis of paraffin-embedded human bladder Cancer tissues using Jurkat mouse mAb with DAB staining.

免疫沉淀（IP）

免疫组织化学（IHC）