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CD220 monoclonal antibody

货号: MB23243

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB23243

Product Name :CD220 monoclonal antibody

Swiss-Prot :P06213

Host :Mouse

Reactivity :Human, Mouse, Monkey

Applications :WB,IF,FCM

Application_all :WB:1/500 - 1/2000 IF:1/50 - 1/200 FC:1/200 - 1/400

Background :This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants.</p>

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG2a

BiowMW :156kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :INSR; HHF5

Immunogen :Purified recombinant fragment of human CD220 (AA: extra 413-624) expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using CD220 mouse mAb against HepG2 (1), HEK293 (2), Jurkat (3), Hela (4), THP-1 (5), NIH/3T3 (6), COS7 (7), and PC-3 (8) cell lysate.

Immunofluorescence analysis of Hela cells using CD220 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)