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p21 polyclonal antibody

货号: BZ16025

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BZ16025

Product Name :p21 polyclonal antibody

Swiss-Prot :P38936

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC IF/ICC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:100 IF/ICC: 1:50~1:200

Background :The tumor suppressor protein p21 Waf1/Cip1 acts as an inhibitor of cell cycle progression. It functions in stoichiometric relationships forming heterotrimeric complexes with cyclins and cyclin-dependent kinases. In association with CDK2 complexes, it serves to inhibit kinase activity and block progression through G1/S. However, p21 may also enhance assembly and activity in complexes of CDK4 or CDK6 and cyclin D.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :p21 polyclonal antibody detects endogenous levels of p21 protein.

BiowMW :~ 21 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CAP20; CDKN1; CIP1; MDA6; PIC1; SDI1; WAF1; Cyclin-dependent kinase inhibitor 1; CDK-interacting protein 1; Melanoma differentiation-associated protein 6; MDA-6; p21

Immunogen :Recombinant protein corresponding to human p21.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of p21 expression in 293T (A), MCF7 (B), mouse liver (C), Hela (D) whole cell lysates.

Immunohistochemical analysis of p21 staining in human breast cancer formalin fixed paraffin embedded tissue section.

Immunofluorescent analysis of p21 staining in A549 cells.

Integrated Bioinformatic Analysis and Experimental Validation for Crosstalk Among Various Forms of Cell Death in Spinal Cord Injury

JournalMOLECULAR NEUROBIOLOGY

ApplicationIF,WB

IF4.3

SpeciesMouse

PMID41405788