Product Name :KDM5B polyclonal antibody
Reactivity :Human, Mouse, Rat
Application_all :WB: 1:1000-1:2000
ICC/IF: 1:20-1:100
Background :PLU-1 is a large (1,544 amino acid) nuclear protein that interacts with brain factor-1 (BF-1) and paired box 9 (PAX9), both of which are developmental transcription factors. PLU-1 belongs to the testis-cancer antigen group of proteins and is a member of the ARID family of DNA binding proteins. It is a multi-domain protein with strong transcriptional repression properties. PLU-1 shows restricted expression in adult tissues, with high expression in testis and transient expression in the pregnant mammary gland. Both the PLU-1 gene and the PLU-1 protein product are specifically upregulated in breast cancer. PLU-1 may be important in meiotic transcription because of its apparent association with chromatin.
Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :Peptide affinity purified
Storage&Stability :Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity :KDM5B polyclonal antibody detects endogenous levels of KDM5B protein.
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :CT31, RBP2-H1, KDM5B, JARID1B, PLU1, RBBP2H1, Cancer/testis antigen 31, CT31, Histone demethylase JARID1B, JARID1B, Jumonji AT rich interactive domain 1B, Jumonji/ARID domain-containing protein 1B, Kdm5b, KDM5B, Lysine (K) specific demethylase 5B, Lysine demethylase 5B, Lysine specific demethylase 5B, Lysine-specific demethylase 5B, PLU-1, PLU1, PPP1R98, Protein phosphatase 1 regulatory subunit 98, PUT1, putative DNA/chromatin binding motif, RBBP2H1A, RBP2 like, RBP2-H1, Retinoblastoma-binding protein 2 homolog 1, Retinoblastoma-binding protein 2 homolog 1A,
