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RAMP3 polyclonal antibody

货号: BS8378

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS8378

Product Name :RAMP3 polyclonal antibody

Swiss-Prot :O60896

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB IF/ICC

Application_all :WB: 1:500~1:2000 IF/ICC: 1:50~1:200

Background :The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP3) protein, CRLR functions as an adrenomedullin receptor.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :RAMP3 polyclonal antibody detects endogenous levels of RAMP3 protein.

BiowMW :40kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Receptor activity-modifying protein 3; Calcitonin-receptor-like receptor activity-modifying protein 3; CRLR activity-modifying protein 3; RAMP3

Immunogen :Recombinant fusion protein of human RAMP3(NP_005847.1).

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of RAMP3 expression in MCF7 (A), mouse brain (B), mouse heart (C), rat brain (D), rat lung (E) whole cell lysates.

Immunofluorescent analysis of RAMP3 staining in MCF7 cells.