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PTPRN polyclonal antibody

货号: BS8189

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS8189

Product Name :PTPRN polyclonal antibody

Swiss-Prot :Q16849

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IHC

Application_all :WB,1:500 - 1:2000|IHC,1:50 - 1:200

Background :The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. Alternate splicing results in multiple transcript variants.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :PTPRN polyclonal antibody detects endogenous levels of PTPRN protein.

BiowMW :66kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ICA3; ICA512; Receptor-type tyrosine-protein phosphatase-like N; R-PTP-N; Islet cell antigen 512; ICA 512; Islet cell autoantigen 3; PTP IA-2

Immunogen :Recombinant fusion protein of human PTPRN(NP_001186693.1).

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of PTPRN expression in mouse stomach (A) whole cell lysates.