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SLC7A11 polyclonal antibody

货号: BS79851

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS79851

Product Name :SLC7A11 polyclonal antibody

Swiss-Prot :Q9UPY5

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB

Application_all :WB:1:500 - 1:2000

Background :This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death. xCT has a predicted molecular weight of 55 kDa; however it has a high number of hydrophobic residues which may affect the migration of the protein in SDS-PAGE. Endogenous monomeric xCT is expected to migrate at ~35 kDa and modified-xCT is expected to migrate at ~55 kDa (PMID: 17035536)

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :SLC7A11 polyclonal antibody detects endogenous levels of SLC7A11 protein.

BiowMW :~ 35, 55 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Cystine/glutamate transporter; Amino acid transport system xc-; Calcium channel blocker resistance protein CCBR1; Solute carrier family 7 member 11; xCT

Immunogen :KLH-conjugated synthetic peptide of human SLC7A11.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of SLC7A11 expression in mouse kidney (A), rat liver (B) whole cell lysates.

Soybean Lecithin–Gallic Acid Complex Sensitizes Lung Cancer Cells to Radiation Through Ferroptosis Regulated by Nrf2/SLC7A11/GPX4 Pathway

JournalNutrients

ApplicationWB

IF4.8

SpeciesHuman

PMID40219018
MiR-424-3p suppresses adipogenesis via HNRNPA0 targeting and p53-mediated ferroptosis

JournalBIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

ApplicationWB

IF3.3

SpeciesMouse

PMID41381030