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IκBα polyclonal antibody

货号: BS79667

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS79667

Product Name :IκBα polyclonal antibody

Swiss-Prot :P25963

Host :Rabbit

Reactivity :Human,Mouse,Rat,Bovine,Pig,Sheep

Applications :WB IHC IF/ICC

Application_all :WB: 1:500~1:1000 IHC: 1:100~1:200 IF/ICC: 1:100~1:500

Background :This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IκBα polyclonal antibody detects endogenous levels of IκBα protein.

BiowMW :36kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :IKBA; MAD3; NFKBI; NF-kappa-B inhibitor alpha; I-kappa-B-alpha; IkB-alpha; IkappaBalpha; Major histocompatibility complex enhancer-binding protein MAD3

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human IκBα.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of IκBα expression in rat kidney (A), rat muscle (B) whole cell lysates.

Immunohistochemical analysis of IκBα staining in human breast cancer formalin fixed paraffin embedded tissue section.

Immunofluorescent analysis of IκBα staining in HepG2 cells.