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COMT polyclonal antibody

货号: BS7956

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS7956

Product Name :COMT polyclonal antibody

Swiss-Prot :P21964

Host :Rabbit

Reactivity :Human, Mouse, Rat, Monkey

Applications :WB IF/ICC

Application_all :WB,1:500 - 1:1000|IF/ICC,1:100 - 1:500

Background :Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :COMT polyclonal antibody detects endogenous levels of COMT protein.

BiowMW :~ 30 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Catechol O-methyltransferase

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the center region of human COMT.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of COMT expression in A549 (A), U2OS (B), rat testis (C) whole cell lysates.

Immunofluorescent analysis of COMT staining in Raw264.7 cells.

免疫沉淀（IP）

免疫组织化学（IHC）