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GSTA3 polyclonal antibody

货号: BS77288

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS77288

Product Name :GSTA3 polyclonal antibody

Swiss-Prot :Q16772

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IF/ICC

Application_all :WB,1:500 - 1:2000|IF/ICC,1:50 - 1:200

Background :Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class genes that are located in a cluster mapped to chromosome 6. Genes of the alpha class are highly related and encode enzymes with glutathione peroxidase activity. However, during evolution, this alpha class gene diverged accumulating mutations in the active site that resulted in differences in substrate specificity and catalytic activity. The enzyme encoded by this gene catalyzes the double bond isomerization of precursors for progesterone and testosterone during the biosynthesis of steroid hormones. An additional transcript variant has been identified, but its full length sequence has not been determined. [provided by RefSeq, Jul 2008]

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :GSTA3 polyclonal antibody detects endogenous levels of GSTA3 protein.

BiowMW :25kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Glutathione S-transferase A3; GST class-alpha member 3; Glutathione S-transferase A3-3

Immunogen :Recombinant fusion protein of human GSTA3(NP_000838.3).

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of GSTA3 expression in HEK293T (A), mouse lung (B), mouse liver (C), rat kidney (D) whole cell lysates.

Immunofluorescent analysis of GSTA3 staining in L929 cells.

免疫沉淀（IP）

免疫组织化学（IHC）