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CYP11B2 polyclonal antibody

货号: BS75765

价格：￥ 1140

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS75765

Product Name :CYP11B2 polyclonal antibody

Swiss-Prot :P19099

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IF-P

Application_all :WB,1:1000 - 1:5000|IF-P,1:100 - 1:500

Background :This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CYP11B2 polyclonal antibody detects endogenous levels of CYP11B2 protein.

BiowMW :50kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CYP11B2; ALDOS; CPN2; CYP11B; CYP11BL; CYPXIB2; P-450C18; P450C18; P450aldo; cytochrome P450 11B2; mitochondrial

Immunogen :A synthetic peptide of human CYP11B2.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of lysates from wild type (WT) and 293T cells transfected with CYP11B2 using CYP11B2 pAb at 1:2000 dilution.

Immunofluorescence analysis of paraffin-embedded Human adrenal gland using Rabbit pAb at a dilution of 1:200 (40x lens).

Immunofluorescence analysis of paraffin-embedded Mouse adrenal gland using CYP11B2 pAb at a dilution of 1:200 (40x lens).

Immunofluorescence analysis of paraffin-embedded Rat adrenal gland using CYP11B2 pAb at a dilution of 1:200 (40x lens).