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S100A12 polyclonal antibody

货号: BS7539

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS7539

Product Name :S100A12 polyclonal antibody

Swiss-Prot :P80511

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IHC, IF/ICC

Application_all :WB,1:500 - 1:2000|IHC,1:50 - 1:200|IF/ICC,1:50 - 1:200

Background :The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities. The protein includes an antimicrobial peptide which has antibacterial activity.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :S100A12 polyclonal antibody detects endogenous levels of S100A12 protein.

BiowMW :11KDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Protein S100-A12; CGRP; Calcium-binding protein in amniotic fluid 1; CAAF1; Calgranulin-C; CAGC; Extracellular newly identified RAGE-binding protein; EN-RAGE; Migration inhibitory factor-related protein 6; MRP-6; p6; Neutrophil S100 protein; S100 calcium-binding protein A12

Immunogen :Recombinant fusion protein of human S100A12(NP_005612.1).

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of S100A12 expression in HL60 (A), SW620 (B), K562 (C) whole cell lysates.

Immunohistochemical analysis of S100A12 staining in human lung cancer formalin fixed paraffin embedded tissue section.

Immunofluorescent analysis of S100A12 staining in SW620 cells.