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MMP11 polyclonal antibody

货号: BS7168

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS7168

Product Name :MMP11 polyclonal antibody

Swiss-Prot :P24347

Host :Rabbit

Reactivity :Human, Mouse, Rat, Dog

Applications :WB IHC IF/ICC

Application_all :WB: 1:500~1:1000 IHC: 1:100~1:200 IF/ICC: 1:100~1:500

Background :Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :MMP11 polyclonal antibody detects endogenous levels of MMP11 protein.

BiowMW :60kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :STMY3; Stromelysin-3; SL-3; ST3; Matrix metalloproteinase-11; MMP-11

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the center region of human MMP11.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of MMP11 expression in mouse kidney (A), rat kidney (B) whole cell lysates.

Immunohistochemical analysis of MMP11 staining in human breast cancer formalin fixed paraffin embedded tissue section.

Immunofluorescent analysis of MMP11 staining in Raw264.7 cells.

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