产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

NFAT2 polyclonal antibody

货号: BS6677

价格：￥ 1140

货期：现货（1-2个工作日）

25ug 50ug 100ug 200ug

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS6677

Product Name :NFAT2 polyclonal antibody

Swiss-Prot :O95644

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IHC, IF/ICC

Application_all :WB,1:500 - 1:2000|IHC,1:50 - 1:200|IF/ICC,1:50 - 1:200

Background :The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :NFAT2 polyclonal antibody detects endogenous levels of NFAT2 protein.

BiowMW :~ 74, 101 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :NFAT2; NFATC; Nuclear factor of activated T-cells, cytoplasmic 1; NF-ATc1; NFATc1; NFAT transcription complex cytosolic component; NF-ATc; NFATc

Immunogen :Recombinant fusion protein of human NFAT2(NP_001265598.1).

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of NFAT2 expression in Jurkat (A), HL60 (B) whole cell lysates.

Immunohistochemical analysis of NFAT2 staining in human tonsil formalin fixed paraffin embedded tissue section.

Immunofluorescent analysis of NFAT2 staining in U2OS cells.

Western blot analysis of NFAT2 expression in mouse thymus (A) whole cell lysates.

BTP2, a Store-Operated Calcium Channel Inhibitor, Attenuates Lung Ischemia-Reperfusion Injury in Rats

JournalInflammation

ApplicationWB

IF2.939

SpeciesRat

PMID28168659
TAZ inhibits osteoclastogenesis by attenuating TAK1/NF-κB signaling

JournalBone Research

ApplicationIHC

IF13.567

SpeciesMouse

PMID34253712
Tetrandrine attenuates the bone erosion in collagen-induced arthritis rats by inhibiting osteoclastogenesis via spleen tyrosine kinase

JournalFaseb Journal

ApplicationWB,IF

IF5.391

SpeciesMouse

PMID29401630
The protective effect of WKYMVm peptide on inflammatory osteolysis through regulating NF-κB and CD9/gp130/STAT3 signalling pathway

JournalJournal Of Cellular And Molecular Medicine

ApplicationWB

IF5.31

SpeciesMouse

PMID31837208
Dual effects of baicalin on osteoclast differentiation and bone resorption

JournalJournal Of Cellular And Molecular Medicine

ApplicationWB

IF4.658

SpeciesMouse

PMID30010244