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AMPK alpha 1/2 polyclonal antibody

货号: BS66251

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS66251

Product Name :AMPK alpha 1/2 polyclonal antibody

Swiss-Prot :Q13131/P54646

Host :Rabbit

Reactivity :Human, Mouse, Rat, Chicken, Pig

Applications :WB, IHC, IF/ICC

Application_all :WB,1:500 - 1:1000|IHC,1:50 - 1:200|IF/ICC,1:50 - 1:200

Background :The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :AMPK alpha 1/2 polyclonal Antibody detects endogenous levels of AMPK alpha 1/2 protein.

BiowMW :~ 63 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :PRKAA1; AMPK1; 5'-AMP-activated protein kinase catalytic subunit alpha-1; AMPK subunit alpha-1; Acetyl-CoA carboxylase kinase; ACACA kinase; Hydroxymethylglutaryl-CoA reductase kinase; HMGCR kinase; Tau-protein kinase PRKAA1; PRKAA2; AMPK; AMPK2; 5'-AMP-activated protein kinase catalytic subunit alpha-2; AMPK subunit alpha-2; Acetyl-CoA carboxylase kinase; ACACA kinase; Hydroxymethylglutaryl-CoA reductase kinase; HMGCR kinase

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the center region of human AMPK alpha 1/2.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of AMPK alpha 1/2 expression in Hela (A), A549 (B), K562 (C), 3T3L1 (D) whole cell lysates.

Immunohistochemical analysis of AMPK alpha 1/2 staining in human breast cancer formalin fixed paraffin embedded tissue section.

Immunofluorescent analysis of AMPK alpha 1/2 staining in PANC1 cells.