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SNW1 polyclonal antibody

货号: BS66243

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS66243

Product Name :SNW1 polyclonal antibody

Swiss-Prot :Q13573

Host :Rabbit

Reactivity :Human, Mouse

Applications :WB IF/ICC

Application_all :WB,1:500 - 1:1000|IF/ICC,1:10 - 1:50

Background :This gene, a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also function as a splicing factor by interacting with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity. Alternative splicing results in multiple transcript variants.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :SNW1 polyclonal antibody detects endogenous levels of SNW1 protein.

BiowMW :~ 61 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :SKIIP; SKIP; SNW domain-containing protein 1; Nuclear protein SkiP; Nuclear receptor coactivator NCoA-62; Ski-interacting protein

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the Central region of human SNW1.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of SNW1 expression in 293T (A), A431 (B), Hela (C), HepG2 (D), NIH3T3 (E) whole cell lysates.

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）