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CD144 Recombinant Rabbit mAb

货号: BS66239

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS66239

Product Name :CD144 Recombinant Rabbit mAb

Swiss-Prot :P55284

Host :Rabbit

Reactivity :Mouse, Rat

Applications :WB, IHC, IF/ICC, IP

Application_all :WB,1:500 - 1:1000|IHC,1:50 - 1:200|IF/ICC,1:50 - 1:200|IP,1:10 - 1:50

Background :The cadherins are a family of Ca 2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy-terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including β-catenin, to regulate cadherin function. VE-cadherin (for vascular endothelial cadherin, also designated cadherin-5) is localized at intercellular junctions of endothelial cells, where it is thought to play a role in the cohesion and organization of intercellular junctions.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CD144 Recombinant Rabbit mAb detects endogenous levels of CD144 protein.

BiowMW :~ 90-140 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Cadherin-5; 7B4 antigen; Vascular endothelial cadherin; VE-cadherin; CD144

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within mouse CD144 protein.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of CD144 expression in mouse lung (A) whole cell lysates.

Immunohistochemical analysis of CD144 staining in rat lung formalin fixed paraffin embedded tissue section.