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LAMP2 polyclonal antibody

货号: BS66238

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS66238

Product Name :LAMP2 polyclonal antibody

Swiss-Prot :P13473

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IF/ICC

Application_all :WB: 1:500~1:1000 IF/ICC: 1:50~1:200

Background :Lysosome-associated membrane proteins (LAMP) are glycosylated type I membrane proteins that play a role in the biogenesis of the pigment melanin. LAMP-1 (also designated CD107A) and LAMP-2 (also designated CD107B) are involved in a variety of functions, including cellular adhesion, and are thought to participate in the process of tumor invasion and metastasis. Newly synthesized LAMP-1 and LAMP-2 proteins are sorted at the trans Golgi network and are transported intracellularly via a pathway that is distinct from the clathrin-coated vesicles used for the mannose-6 phosphate receptor. LAMP-1 is expressed on the surface of thrombin-activated but not resting platelets, and it is thought to be involved in the adhesive, prothrombic properties of these cells. Both LAMP-1 and LAMP-2 are involved in maintaining lysosome acidity and protecting the lysosomal membranes from autodigestion, and their expression is increased in patients with lysosomal storage disorders.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :LAMP2 polyclonal antibody detects endogenous levels of LAMP2 protein.

BiowMW :~ 100, 44 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Lysosome-associated membrane glycoprotein 2; LAMP-2; Lysosome-associated membrane protein 2; CD107 antigen-like family member B; CD107b

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the center region of human LAMP2.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of LAMP2 expression in A375 (A), DLD (B), mouse lung (C), mouse liver (D), rat lung (E), rat liver (F) whole cell lysates.