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MyD88 Polyclonal Antibody

货号: BS65652

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS65652

Product Name :MyD88 Polyclonal Antibody

Swiss-Prot :Q99836

Host :Rabbit

Reactivity :Human,Mouse,Rat, Bovine, Monkey, Pig, Sheep

Applications :WB IHC IF/ICC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200 IF/ICC: 1:100~1:500

Background :This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010].

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :MyD88 Polyclonal Antibody detects endogenous levels of MyD88 protein.

BiowMW :~ 33, 31, 28 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Myeloid differentiation primary response protein MyD88

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the center region of human MYD88.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of MYD88 expression in HEK293T (A), Hela (B), mouse lung (C), mouse muscle (D), mouse spleen (E), rat muscle (F), rat spleen (G) whole cell lysates.

Immunohistochemical analysis of MYD88 staining in human brain formalin fixed paraffin embedded tissue section.

Immunofluorescent analysis of MYD88 staining in Jurkat cells.

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