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GDF15 polyclonal antibody

货号: BS6152

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS6152

Product Name :GDF15 polyclonal antibody

Swiss-Prot :Q99988

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IHC, IF/ICC, IP

Application_all :WB,1:500 - 1:1000|IHC,1:50 - 1:200|IF/ICC,1:50 - 1:200|IP,1:50 - 1:100

Background :The protein encoded by this gene belongs to the transforming growth factor-beta (TGF-beta) family. The protein is expressed in a broad range of cell types, acts as a pleiotropic cytokine and is involved in the stress reponse program of cells after cellular injury. Increased protein levels are associated with disease states such as tissue hypoxia, inflammation, acute injury and oxidative stress.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :GDF15 polyclonal antibody detects endogenous levels of GDF15 protein.

BiowMW :35KDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :MIC1; PDF; PLAB; PTGFB; Growth/differentiation factor 15; GDF-15; Macrophage inhibitory cytokine 1; MIC-1; NSAID-activated gene 1 protein; NAG-1; NSAID-regulated gene 1 protein; NRG-1; Placental TGF-beta; Placental bone morphogenetic protein; Prostate differentiation factor

Immunogen :Recombinant fusion protein of human GDF15(NP_004855.2).

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of GDF15 expression in HT1080 (A) whole cell lysates.

Immunohistochemical analysis of GDF15 staining in human placenta formalin fixed paraffin embedded tissue section.

Immunofluorescent analysis of GDF15 staining in 3T3 cells.

Growth differentiation factor 15 contributes to cancer-associated fibroblasts-mediated chemo-protection of AML cells

JournalJournal Of Experimental & Clinical Cancer Research

ApplicationWB

IF7.068

SpeciesHuman

PMID27643489