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NRG1 polyclonal antibody

货号: BS6037

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS6037

Product Name :NRG1 polyclonal antibody

Swiss-Prot :Q02297

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IF/ICC

Application_all :WB: 1:500~1:1000 IF/ICC: 1:50~1:200

Background :Neuregulin-1 gene, NRG1, encodes numerous splice variants with differing transcription initiation sites. Neuregulin-1 includes a range of isoforms with varying glycosylation, regulation of expression and function. Neuregulin-1 splice variants each bear an EGF-like domain, though otherwise have unique domain structures, differing functions and discrete tissue distribution. Six types of Neuregulin-1 isoform groups have been defined based on their structural features. Three types are most often described, type I (ARIA, NDF or HRG), type II (GGF) and type III (SMDF). Neuregulin-1 has been linked to schizophrenia and has diverse neural functions. Neuregulin-1 affects cell migration, the differentiation of neural crest and Schwann cells, and acts to upregulate the expression of acetylcholine receptors at muscle fibers during the formation of neuromuscular junctions.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :NRG1 polyclonal antibody detects endogenous levels of NRG1 protein.

BiowMW :~ 70, 45 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :GGF; HGL; HRGA; NDF; SMDF; Pro-neuregulin-1, membrane-bound isoform; Pro-NRG1

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human NRG1.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of NRG1 expression in mouse liver (A), mouse spleen (B), rat liver (C), rat spleen (D) whole cell lysates.

Immunofluorescent analysis of NRG1 staining in A549 cells.

免疫沉淀（IP）

免疫组织化学（IHC）