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HXK I / HK1 monoclonal antibody

货号: MB0140

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :MB0140

Product Name :HXK I / HK1 monoclonal antibody

Swiss-Prot :P19367

Host :Mouse

Reactivity :Human

Applications :WB ICC

Application_all :WB: 1:1000~10000 ICC: 1:100~500

Background :Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus; the remainder of the protein is identical among all the isoforms. A sixth transcript variant has been described, but due to the presence of several stop codons, it is not thought to encode a protein.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :This antibody detects endogenous levels of Hexokinase-1 and does not cross-react with related proteins

BiowMW :Predicted band size:102kDa Observed band size:102kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Warburg Effect,Insulin &Glucose Signaling,Glutamine Metabolism,

Alternative Name :Hexokinase-1; Hexokinase 1; Brain form hexokinase; Hexokinase type I; HK I; HK1

Immunogen :Recombinant full length Human HXK I.

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of HK1 in Hela&Jurkat cell lysates using HK1 antibody (1:10000 diluted) .

免疫沉淀（IP）

免疫组织化学（IHC）