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CDX2 monoclonal antibody

货号: MB0125

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :MB0125

Product Name :CDX2 monoclonal antibody

Swiss-Prot :Q99626

Host :Mouse

Reactivity :Human,Monkey,Mouse

Applications :WB IP ICC

Application_all :WB: 1:1000 ICC: 1:100 IP: 1:50~1:200

Background :This gene is a member of the caudal-related homeobox transcription factor gene family.The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation.This protein also plays a role in early embryonic development of the intestinal tract.Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis. Involved in the transcriptional regulation of multiple genes expressed in the intestinal epithelium.Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CDX2 mAb detects endogenous levels of CDX2 protein.

BiowMW :Predicted band size:34KDa Observed band size:34KDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Caudal type homeo box 2; Caudal type homeo box transcription factor 2; Caudal type homeobox 2; Caudal type homeobox protein 2; caudal type homeobox transcription factor 2; Caudal-type homeobox protein 2; CDX 2; CDX 3; CDX-3; Cdx2; CDX2; CDX3; Homeobox protein CDX 2; Homeobox protein CDX-2; Homeobox protein CDX2

Immunogen :Recombinant full length Human CDX2.

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of CDX2 in Hela, Caco2, C2C12, SW480, COS7, HepG2 & 3T3 cell lysates using CDX2 antibody (1:1000 diluted) .

Immunocytochemistry stain of Hela using CDX2 antibody (1:100).

Chemopreventive activity of GEN-27, a genistein derivative, in colitis-associated cancer is mediated by p65-CDX2-β-catenin axis

JournalOncotarget

ApplicationWB

IF0

SpeciesHuman

PMID26910375