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Hexokinase-2 ( N-term) monoclonal antibody

货号: MB0103

价格：￥ 1350

货期：现货（1-2个工作日）

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No. :MB0103

Product Name :Hexokinase-2 ( N-term) monoclonal antibody

Swiss-Prot :P52789

Host :Mouse

Reactivity :Human,Rat

Applications :WB FC

Application_all :WB: 1:1000 FC: 1:50~100

Background :Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :This antibody detects endogenous levels of Hexokinase-2 and does not cross-react with related proteins

BiowMW :Predicted band size:102KDa Observed band size:102KDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Warburg Effect,Insulin &Glucose Signaling,Glutamine Metabolism,

Alternative Name :Hexokinase 2; Hexokinase2; Hexokinase type II; HK II; Muscle form hexokinase; HK2

Immunogen :Synthetic peptide, corresponding to amino acids N-terminus of Human Hexokinase-2.

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of Hexokinase-2 (N-terminus) antibody in PC12, Hela&Jurkat lysates using Hexokinase-2 (N-terminus) antibody (1:1000 diluted) .

Flow Cytometry analysis of K562 cells stained with Hexokinase-2(N-terminus) (red, 1/100 dilution), followed by FITC-conjugated goat anti-mouse IgG. Blue line histogram represents the isotype control, normal mouse IgG.