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KMT6 polyclonal antibody

货号: BZ16737

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BZ16737

Product Name :KMT6 polyclonal antibody

Swiss-Prot :Q15910

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB,IHC,ICC/IF,IP

Application_all :WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/50-1/100

Background :Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Compared to EZH2-containing complexes, it is more abundant in embryonic stem cells and plays a major role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :KMT6 polyclonal antibody detects endogenous levels of KMT6 protein.

BiowMW :~ 98 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :KMT6; Histone-lysine N-methyltransferase EZH2; ENX-1; Enhancer of zeste homolog 2; Lysine N-methyltransferase 6

Immunogen :Recombinant fusion protein of human KMT6.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of KMT6 expression in HL60 (A), SW620 (B), MCF7 (C), mouse ovary (D) whole cell lysates.

Immunohistochemical analysis of KMT6 staining in human thyroid cancer formalin fixed paraffin embedded tissue section.

Immunofluorescent analysis of KMT6 staining in KYSE150 cells.

Immunoprecipitation of KMT6 from 0.5mg Hela whole cell extract lysate, using Anti-EZH2 Antibody.