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GLUL polyclonal antibody

货号: BZ00935

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BZ00935

Product Name :GLUL polyclonal antibody

Swiss-Prot :P15104

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC IP FC

Application_all :WB: 1:500-1:2000 IHC: 1:50-1:200 IP/FC: 1:50

Background :Glutamine synthetase (GI Syn) forms a homooctamer that serves as a catalyst for the amination of glutamic acid to form glutamine. This enzyme is a marker for astrocytes, which serve as the primary site of conversion of glutamic acid to glutamine in the brain. Induction of glutamine synthetase is seen upon astrocyte cell contact with neurons. Elevated expression of glutamine synthetase in glial cells has been shown to protect neurons from degeneration due to excess glutamate. Glutamine synthetase is also present in the liver and is involved in nitrogen homeostasis. Overexpression of glutamine synthetase has been shown in primary liver cancers, indicating a potential role for glutamine synthetase in hepatocyte transformation.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Glutamine Synthetase Antibody detects endogenous levels of total Glutamine Synthetase.

BiowMW :~ 49 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Glutamine Metabolism,

Alternative Name :Glutamine synthetase; GS; Glutamate decarboxylase; Glutamate--ammonia ligase; GLNS; Gl Syn

Immunogen :A synthesized peptide derived from human Glutamine Synthetase.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of Glutamine Synthetase expression in (1)Jurkat cell lysate;(2) HeLa cell lysate.

免疫沉淀（IP）

免疫组织化学（IHC）