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eRF3a (D128) polyclonal antibody（KU）

货号: BS9137

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS9137

Product Name :eRF3a (D128) polyclonal antibody（KU）

Swiss-Prot :P15170

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :eRF3a (eukaryotic peptide chain release factor subunit 3a), also known as GSPT1 (G1 to S phase transition 1), is a 499 amino acid protein that belongs to the GTP-binding elongation factor family and is involved in the regulation of cell growth, specifically via control of translation termination. Human eRF3a shares 94% sequence identity with its mouse counterpart, suggesting a conserved function between species. The gene encoding eRF3a maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :eRF3a (D128) polyclonal antibody detects endogenous levels of eRF3a protein.

BiowMW :~ 80 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Eukaryotic peptide chain release factor GTP-binding subunit ERF3A; Eukaryotic peptide chain release factor subunit 3a; eRF3a; G1 to S phase transition protein 1 homolog; GSPT1; ERF3A

Immunogen :Synthetic peptide, corresponding to amino acids 100-150 of Human eRF3a.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of eRF3a (D128) pAb at 1:500 dilution Lane1:SGC7901 whole cell lysate(40ug) Lane2:Panc1 whole cell lysate(40ug) Lane3:PC3 whole cell lysate(40ug) Lane4:AML-12 whole cell lysate(40ug) Lane5:PC12 whole cell lysate(40ug)

Immunohistochemistry (IHC) analyzes of eRF3a (D128) pAb in paraffin-embedded human colorectal carcinoma tissue at 1:50.