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HSF1 (S303) polyclonal antibody

货号: BS9117

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS9117

Product Name :HSF1 (S303) polyclonal antibody

Swiss-Prot :Q00613

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Heat shock transcription factors (HSF, also designated HSTF) 1 and 2 are involved in this regulation. HSF1 and HSF2 are upregulated by estrogen at both the mRNA and protein level. HSF1 is normally found as a monomer whose transcriptional activity is repressed by constitutive phosphorylation. Upon activation, HSF1 forms trimers, gains DNA binding activity and is translocated to the nucleus. HSF2 activity is associated with differentiation and development, and, like HSF1, binds DNA as a trimer. Both HSF1 and HSF2 are known to be induced by proteasome inhibitors of the ubiquitin pathway.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :HSF1 (S303) polyclonal antibody detects endogenous levels of HSF1 protein.

BiowMW :~ 82 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Heat shock factor 1; Heat shock factor protein 1; Heat shock transcription factor 1; HSF 1; hsf1; HSF1; HSTF 1; HSTF1;

Immunogen :Synthetic peptide, corresponding to amino acids 270-315 of Human HSF1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of HSF1 polyclonal antibody at 1:1000 dilution Lane1:HELA whole cell lysate(41ug) Lane2:DLD whole cell lysate(37ug) Lane3:NIH3T3 whole cell lysate(48ug) Lane4:H9C2 whole cell lysate(37ug)