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HNRNPA1 polyclonal antibody

货号: BS8947

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS8947

Product Name :HNRNPA1 polyclonal antibody

Swiss-Prot :P09651

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC IF

Application_all :WB: 1:500~1:2000 IHC: 1:50~1:200

Background :HnRNP A1 belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre mRNAs in the nucleus and appear to influence pre mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. hnRNP A1 has two repeats of quasi RRM domains that bind to RNAs. It is one of the most abundant core proteins of hnRNP complexes and it is localized to the nucleoplasm. This protein, along with other hnRNP proteins, is exported from the nucleus, probably bound to mRNA, and is immediately re imported.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :HNRNPA1 polyclonal antibody detects endogenous levels of HNRNPA1 protein.

BiowMW :~ 39kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :hnRNP core protein A1-like protein; RP11-78J21.1

Immunogen :Recombinant full length Human HNRNPA1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of extracts of various cell lines, using HNRNPA1 antibody.

microRNA-451-modulated hnRNP A1 takes a part in granulocytic differentiation regulation and acute myeloid leukemia

JournalOncotarget

ApplicationWB

IF0

SpeciesHuman

PMID28903433