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G3BP1 polyclonal antibody

货号: BS8472

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS8472

Product Name :G3BP1 polyclonal antibody

Swiss-Prot :Q13283

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB, IHC, IF/ICC

Application_all :WB,1:500 - 1:1000|IHC,1:100 - 1:200|IF/ICC,1:100 - 1:500

Background :G3BP is one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :G3BP1 polyclonal antibody detects endogenous levels of G3BP1 protein.

BiowMW :~ 70 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :G3BP1; G3BP; hDH VIII; G3BP-1; Ras GTPase-activating protein-binding protein 1; GAP SH3 domain-binding protein 1

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the center region of human G3BP1.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of G3BP1 expression in A375 (A), DLD (B) whole cell lysates.

Immunohistochemical analysis of G3BP1 staining in human breast cancer formalin fixed paraffin embedded tissue section.

Immunofluorescent analysis of G3BP1 staining in A549 cells.

免疫沉淀（IP）