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GPD2 polyclonal antibody

货号: BS8295
价格 1140
货期 现货(1-2个工作日)
25ul 50ul 100ul 200ul
No. :BS8295
Product Name :GPD2 polyclonal antibody
Swiss-Prot :P43304
Host :Rabbit
Reactivity :Human,Mouse,Rat
Applications :WB IHC
Application_all :WB: 1:500~1:2000 IHC: 1:50~1:200
Background :GPD2 (glycerol-3-phosphate dehydrogenase 2, mitochondrial), also known as GDH2 or GPDM, is a 727 amino acid protein belonging to the FAD-dependent glycerol-3-phosphate dehydrogenase family. GPD2 is involved in the conversion of glycerol-3-phosphate (G-3-P) to dihydroxyacetone phosphate (DHAP) while reducing enzyme-bound FAD. Localizing to the outer surface of the inner mitochondrial membrane, GPD2 acts in conjunction with GPD1 (a cytosolic NAD-linked GPD) to form a glycerol phosphate shuttle that ultimately results in the reoxidation of NADH formed during glycolysis. While widely expressed in adult and fetal tissue, GPD2 is found at highest levels in human pancreatic islets where it is essential for pancreatic B-cell glucose-sensory function. Decreased levels of GPD2 leads to impaired glucose-stimulated insulin release in noninsulin-dependent diabetes mellitus. Existing as two alternatively spliced isoforms, GPD2 contains two EF-hand domains and maps to human chromosome 2q24.1.
Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :GPD2 polyclonal antibody detects endogenous levels of GPD2 protein.
BiowMW :~ 81 kDa
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :Glycerol-3-phosphate dehydrogenase, mitochondrial; GPD-M; GPDH-M; mtGPD; GPD2
Immunogen :Recombinant fusion protein containing a sequence corresponding to amino acids 25-325 of human GPD2 (NP_000399.3).
Conjugate :Unconjugated
Modification :Unmodification
Western blot analysis of extracts of various cell lines, using GPD2 Rabbit pAb at 1:1000 dilution.

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400-660-9091

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com