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Fibronectin 1 polyclonal antibody

货号: BS72650

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS72650

Product Name :Fibronectin 1 polyclonal antibody

Swiss-Prot :P02751

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB,IHC,IF

Application_all :WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Background :This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. The encoded preproprotein is proteolytically processed to generate the mature protein. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants, at least one of which encodes an isoform that undergoes proteolytic processing. The full-length nature of some variants has not been determined.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Fibronectin 1 polyclonal antibody detects endogenous levels of Fibronectin 1 protein.

BiowMW :290kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Fibronectin; Cold-insoluble globulin; Short name=CIG; Cleaved into the following 4 chains: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3; FN1; FN

Immunogen :Recombinant protein of human FN1

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of extracts of various cell lines, using FN1 antibody.

Immunohistochemistry of paraffin-embedded rat ovary using FN1 antibody.

Hypoxia Stimulates the Epithelial–to–Mesenchymal Transition in Lung Cancer Cells Through Accumulation of Nuclear β-Catenin

JournalAnticancer Research

ApplicationWB

IF1.994

SpeciesHuman

PMID30396950
Mesenchymal Stem Cell-derived Exosomes Attenuate Epithelial-mesenchymal Transition of HK-2 cells

JournalTissue Engineering Part A

ApplicationWB

IF3.845

SpeciesHuman

PMID35019728
Knockout of KLF10 Ameliorated Diabetic Renal Fibrosis via Downregulation of DKK-1

JournalMOLECULES

ApplicationIHC

IF4.412

SpeciesMouse

PMID35565995
Dickkopf-1 Acts as a Profibrotic Mediator in Progressive Chronic Kidney Disease

JournalINTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

ApplicationIHC

IF6.208

SpeciesRat

PMID37108841