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Cyclin E2 polyclonal antibody

货号: BS71898

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS71898

Product Name :Cyclin E2 polyclonal antibody

Swiss-Prot :O96020

Host :Rabbit

Reactivity :Human

Applications :WB IF

Application_all :WB 1:500 - 1:2000 IF 1:50 - 1:200

Background :The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2. This cyclin has been shown to specifically interact with CIP/KIP family of CDK inhibitors, and plays a role in cell cycle G1/S transition. The expression of this gene peaks at the G1-S phase and exhibits a pattern of tissue specificity distinct from that of cyclin E1. A significantly increased expression level of this gene was observed in tumor-derived cells.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Cyclin E2 polyclonal antibody detects endogenous levels of Cyclin E2 protein.

BiowMW :47kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :G1/S-specific cyclin-E2; CCNE2

Immunogen :Recombinant protein of human CCNE2

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of extracts of Jurkat cells, using CCNE2 antibody (AS014) at 1:10000 dilution.

Expression of cyclin E in postmitotic neurons during development and in the adult mouse brain

JournalGene Expression Patterns

ApplicationIHC

IF0.897

SpeciesMouse

PMID20863901