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AFP polyclonal antibody

货号: BS71768

价格：￥ ——

货期：现货（1-2个工作日）

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No. :BS71768

Product Name :AFP polyclonal antibody

Swiss-Prot :P02771

Host :Rabbit

Reactivity :Mouse,Rat

Applications :WB,IF

Application_all :WB 1:500 - 1:2000 IF 1:50 - 1:200

Background :This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :AFP polyclonal antibody detects endogenous levels of AFP protein.

BiowMW :~ 68 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :AFPD; FETA; HPAFP

Immunogen :Recombinant protein of human AFP

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of extracts of various cell lines, using AFP antibody.

Enhancement of DEN-induced liver tumourigenesis in hepatocyte-specific Lass2-knockout mice coincident with upregulation of the TGF-β1-Smad4-PAI-1 axis

JournalOncology Reports

ApplicationWB

IF3.041

SpeciesMouse

PMID24337404
Decellularized spleen matrix for reengineering functional hepatic-like tissue based on bone marrow mesenchymal stem cells

JournalOrganogenesis

ApplicationIF

IF2.321

SpeciesRat

PMID27158925
Combinatorial treatment of Rhizoma Paridis saponins and sorafenib overcomes the intolerance of sorafenib

JournalJournal Of Steroid Biochemistry And Molecular Biology

ApplicationWB

IF3.785

SpeciesMouse

PMID29932973