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IFI-16 polyclonal antibody

货号: BS7139

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS7139

Product Name :IFI-16 polyclonal antibody

Swiss-Prot :Q16666

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Interferon-gamma inducible protein 16 (IFI16) belongs to the HIN-200 family of transcriptional regulator linked to cell cycle regulation and differentiation by modulating the activities of multiple transcriptional factors, such as p53 and Rb. The HIN-200 (hematopoeitic interferon-inducible nuclear antigens with 200 amino acid repeat) family members contain a DNA binding domain, a transcriptional regulatory domain, DAPIN/PAAD domain associated with interferon response and a binding domain for BRCA1. IFI16 may have a role in the regulation of hematopoeitic cell differentiation and also be involved in DNA repair since it becomes a component of the DNA repair multi-protein BASC complex after UV-induced DNA damage. IFI16 is strongly induced by gamma interferon in vivo.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IFI-16 polyclonal antibody detects endogenous levels of IFI-16 protein.

BiowMW :~ 88 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Inflammasonme Signaling,

Alternative Name :Gamma-interferon-inducible protein Ifi-16; Interferon-inducible myeloid differentiation transcriptional activator; IFI16; IFNGIP1

Immunogen :Synthetic peptide, corresponding to Human IFI-16.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of IFI-16 polyclonal antibody at 1:500 dilution Lane1:Hela whole cell lysate(40ug) Lane2:HepG2 whole cell lysate(40ug)

免疫沉淀（IP）

免疫组织化学（IHC）