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HMGB1 polyclonal antibody

货号: BS7131

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS7131

Product Name :HMGB1 polyclonal antibody

Swiss-Prot :P09429

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC IF

Application_all :WB: 1:500~1:2000 IHC/IF: 1:50~1:200

Background :High mobility group (HMG) proteins 1 and 2 are ubiquitous non-histone components of chromatin. Research suggests that the binding of HMG proteins to DNA induces alterations in the DNA architecture, including DNA bending and unwinding of the helix. HMG proteins synergize with Oct-2, ATF-2, c-Jun and members of the NFκB family to activate transcription.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :HMGB1 polyclonal antibody detects endogenous levels of HMGB1 protein.

BiowMW :~25 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :High mobility group protein B1; High mobility group protein 1; HMG-1; HMGB1; HMG1

Immunogen :Recombinant full length Human HMGB1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of HMGB1 polyclonal antibody

Immunohistochemistry (IHC) analysis of HMGB1 polyclonal antibody in paraffin-embedded Human Embryo Brain tissue.

Curcumin improves memory deficits by inhibiting HMGB1-RAGE/TLR4-NF-κB signalling pathway in APPswe/PS1dE9 transgenic mice hippocampus

JournalJournal Of Cellular And Molecular Medicine

ApplicationWB

IF5.31

SpeciesMouse

PMID34405526
High-mobility group box-1 promotes vascular calcification in diabetic mice via endoplasmic reticulum stress

JournalJournal Of Cellular And Molecular Medicine

ApplicationWB

IF5.31

SpeciesMouse

PMID33724642
Ulinastatin protects rats from sepsis‐induced acute lung injury by suppressing the JAK‐STAT3 pathway

JournalJournal Of Cellular Biochemistry

ApplicationIHC

IF4.237

SpeciesRat

PMID30242880
Methionine enkephalin (MENK) suppresses lung cancer by regulating the Bcl-2/Bax/caspase-3 signaling pathway and enhancing natural killer cell-driven tumor immunity

JournalInternational Immunopharmacology

ApplicationWB,IF

IF3.943

SpeciesHuman,Mouse

PMID34116288
High Mobility Group B-1 (HMGB-1) Promotes Apoptosis of Macrophage-Derived Foam Cells by Inducing Endoplasmic Reticulum Stress

JournalCellular Physiology And Biochemistry

ApplicationWB,IF

IF0

SpeciesMouse

PMID30041247