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ALOXE3 polyclonal antibody

货号: BS71134

价格：￥ ——

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS71134

Product Name :ALOXE3 polyclonal antibody

Swiss-Prot :Q9BYJ1

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IF

Application_all :WB: 1:500~1:2000 IF: 1:50~1:200

Background :This gene is a member of the lipoxygenase family, which are catabolized by arachidonic acid-derived compounds. The encoded enzyme is a hydroperoxide isomerase that synthesizes a unique type of epoxy alcohol (8R-hydroxy-11R,12R-epoxyeicosa-5Z,9E,14Z-trienoic acid) from 12R-hydroperoxyeicosatetraenoic acid (12R-HPETE). This epoxy alcohol can activate the the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha), which is implicated in epidermal differentiation. Loss of function of the enzyme encoded by this gene results in ichthyosis, implicating the function of this gene in the differentiation of human skin. This gene is part of a cluster of lipoxygenase genes on 17p13.1. Mutations in this gene result in nonbullous congenital ichthyosiform erythroderma (NCIE). Multiple transcript variants encoding different isoforms have been found for this gene.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :ALOXE3 polyclonal antibody detects endogenous levels of ALOXE3 protein.

BiowMW :~ 81 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ARCI3; E-LOX; eLOX3; eLOX-3;

Immunogen :Recombinant protein of human ALOXE3.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of extract of various cells, using ALOXE3 antibody.

Prognostic and Predictive Models for Left- and Right- Colorectal Cancer Patients: A Bioinformatics Analysis Based on Ferroptosis-Related Genes.

JournalFrontiers in Oncology

ApplicationIHC

IF6.244

SpeciesHuman

PMID35265525