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GSTA2 polyclonal antibody

货号: BS70857

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS70857

Product Name :GSTA2 polyclonal antibody

Swiss-Prot :P09210

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB 1:500 - 1:2000 IHC 1:50 - 1:200

Background :Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :GSTA2 polyclonal antibody detects endogenous levels of GSTA2 protein.

BiowMW :~ 26 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :GST2; GTA2; GTH2; GSTA2-2;

Immunogen :Recombinant protein of human GSTA2.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of extracts of various cells, using GSTA2 antibody.

Immunohistochemistry of paraffin-embedded human prostate cancer using GSTA2 antibody at dilution of 1:100 (x40 lens).

免疫沉淀（IP）

免疫组织化学（IHC）