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CYP3A5 polyclonal antibody

货号: BS70851

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS70851

Product Name :CYP3A5 polyclonal antibody

Swiss-Prot :P20815

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB 1:500 - 1:2000

Background :This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein metabolizes drugs as well as the steroid hormones testosterone and progesterone. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Two pseudogenes of this gene have been identified within this cluster on chromosome 7. Expression of this gene is widely variable among populations, and a single nucleotide polymorphism that affects transcript splicing has been associated with susceptibility to hypertensions. Alternative splicing results in multiple transcript variants.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CYP3A5 polyclonal antibody detects endogenous levels of CYP3A5 protein.

BiowMW :~ 68 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CP35; PCN3; CYPIIIA5; P450PCN3;

Immunogen :Recombinant protein of human CYP3A5.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of extracts of various cells, using CYP3A5 antibody.

Species Difference in the Metabolism of Mulberrin in Vitro and Its Inhibitory Effect on Cytochrome P450 and UDP-Glucuronosyltransferase Enzymes

JournalCHEMICAL & PHARMACEUTICAL BULLETIN

ApplicationWB

IF1.903

SpeciesHuman

PMID36184449