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Fra-1 polyclonal antibody（KU）

货号: BS70676

价格：￥ 1140

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS70676

Product Name :Fra-1 polyclonal antibody（KU）

Swiss-Prot :P15407

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB IHC IF

Application_all :WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100

Background :The v-Fos oncogene was initially detected in two independent murine osteosarcoma virus isolates and an avian nephroblastoma virus. Members of the c-Fos gene family, including c-Fos, Fos B, Fra-1 and Fra-2, encode nuclear phosphoproteins that are rapidly and transiently induced by a variety of agents and function as transcriptional regulators for several genes. In contrast to c-Jun proteins, which form homo- and heterodimers that bind to specific DNA response elements, c-Fos proteins are only active as heterodimers with members of the Jun gene family. In addition, selected ATF/CREB family members can form leucine zipper dimers with Fos and Jun. Different dimers exhibit differential specificity and affinity for AP-1 and CRE sites.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Fra-1 polyclonal antibody detects endogenous levels of Fra-1 protein.

BiowMW :~ 39 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Fos-related antigen 1; FRA-1; FOSL1; FRA1

Immunogen :Recombinant protein of human FOSL1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of extracts of various cells, using FOSL1 antibody.

Immunofluorescence analysis of HeLa cell using FOSL1 antibody. Blue: DAPI for nuclear staining.

免疫沉淀（IP）

免疫组织化学（IHC）