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Claudin 1 polyclonal antibody

货号: BS6778

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS6778

Product Name :Claudin 1 polyclonal antibody

Swiss-Prot :O95832

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC IF

Application_all :WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Background :The claudin superfamily consists of many structurally related proteins in humans. These proteins are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Three classes of proteins are known to localize to tight junctions, including the claudins, Occludin and junction adhesion molecule (JAM). Claudins, which consist of four transmembrane domains and two extracellular loops, make up tigh junction strands. Emerging evidence suggests that the claudin family of proteins regulates transport through tight junctions via differential discrimination for solute size and charge. Claudin expression is often highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CLDN1 polyclonal antibody detects endogenous levels of CLDN1 protein.

BiowMW :~ 22 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Contribution of ECM and Cytoskeletal Factors to EMT,

Alternative Name :Claudin-1; CLD1; ILVASC; SEMP1; Claudin1; CLDN1; UNQ481/PRO944

Immunogen :Recombinant full length Human Claudin 1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of Claudin 1 polyclonal antibody

Claudin-4 is required for modulation of paracellular permeability by muscarinic acetylcholine receptor in epithelial cells

JournalJournal Of Cell Science

ApplicationWB

IF4.517

SpeciesRat

PMID25948584
Disruption of tight junction structure contributes to secretory dysfunction in IgG4-related sialadenitis

JournalJournal Of Molecular Histology

ApplicationIHC,WB

IF2.611

SpeciesHuman

PMID31865502
Evaluating the State of Glomerular Disease by Analyzing Urinary Sediments: mRNA Levels and Immunofluorescence Staining for Various Markers

JournalINTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

ApplicationIF

IF5.6

SpeciesHuman

PMID38255818