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PLAUR polyclonal antibody

货号: BS66230

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS66230

Product Name :PLAUR polyclonal antibody

Swiss-Prot :Q03405

Host :Rabbit

Reactivity :Mouse, Rat

Applications :WB IHC IF

Application_all :WB: 1:500~1:2000 IHC: 1:100~1:500 IF: 1:100~1:500

Background :This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :PLAUR polyclonal antibody detects endogenous levels of PLAUR protein.

BiowMW :48kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CD87; U-PAR; UPAR; URKR; Par; Plaur3; uPAR-2; uPAR-3; UPAR_HUMAN; PLAUR; Monocyte activation antigen Mo3; MO3; UPAR_MOUSE; UPAR_RAT

Immunogen :A synthetic peptide of human PLAUR.

Conjugate :Unconjugated

Modification :Unmodified

Lane 1: Cerebrum (Mouse) Tissue Lysate at 40 ug Lane 2: Cerebrum (Rat) Tissue Lysate at 40 ug Primary: Anti-PLAUR at 1/1000 dilution

bone (Mouse) Lysate at 40 ug Primary: Anti-PLAUR at 1/300 dilution

Tissue/cell: mouse brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum) at 37℃ for 20 min; Incubation: Anti-PLAUR Polyclonal Antibody, Unconjugated 1:500, overnight at 4°C

Tissue/cell: mouse adrenal gland; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum) at 37℃ for 20 min; Incubation: Anti-PLAUR Polyclonal Antibody, Unconjugated 1:500, overnight at 4°C