Product Name :Calmodulin (Phospho-T80/S82) Polyclonal Antibody
Reactivity :Human,Mouse,Rat,
Applications :WB IF/ICC IHC
Application_all :WB: 1:500-1:1000
IF/ICC: 1:100-1:500
IHC: 1:100-1:200
Background :Calmodulin is a ubiquitously expressed small protein mediating many cellular effects such as short-term and long-term memory, nerve growth, inflammation, apoptosis, muscle contraction and intracellular movement. Upon binding of four Ca2+ ions, calmodulin undergoes conformational changes, allowing this complex to bind to and activate many enzymes including protein kinases, protein phosphatases, ion channels, Ca2+ pumps, nitric oxide synthase, inositol triphosphate kinase, and cyclic nucleotide phosphodiesterase. Since calmodulin binds Ca2+ in a cooperative fashion, small changes in cytosolic Ca2+ levels lead to large changes in the level of active calmodulin and its target proteins.
Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of Calmodulin protein only when phosphorylated at T80/S82.
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :CALM; CAM; CAM1; CAM2; CAMB; CALML2; CAM3; CAMC; CAMIII; Calmodulin; CaM
Immunogen :KLH-conjugated synthetic phosphopeptide corresponding to residues surrounding T80/S82 of human Calmodulin protein.
Modification :Phosphorylation
