产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

Cyclin D1 polyclonal antibody

货号: BS6532

价格：￥ 1350

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS6532

Product Name :Cyclin D1 polyclonal antibody

Swiss-Prot :P24385

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB 1:500 - 1:2000

Background :Considerable effort directed towards the identification of G1 cyclins has led to the isolation of cyclin D, cyclin C and cyclin E. Of these, cyclin D corresponds to a putative human oncogene, designated PRAD1, which maps at the site of the Bcl1 rearrangement in certain lymphomas and leukemias. Two additional human type D cyclins, as well as their mouse homologs, have been identified. Evidence has established that members of the cyclin D family function to regulate phosphorylation of the retinoblastoma gene product, thereby activating E2F transcription factors.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Cyclin D1 polyclonal antibody detects endogenous levels of Cyclin D1 protein.

BiowMW :~ 36 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :G1/S-specific cyclin-D1; B-cell lymphoma 1 protein; BCL-1; BCL-1 oncogene; PRAD1 oncogene; CCND1; BCL1; PRAD1

Immunogen :Recombinant full length Human Cyclin D1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of extracts of various cell lines, using CCND1 antibody at 1:1000 dilution.

Tumorigenic hybrids between mesenchymal stem cells and gastric cancer cells enhanced cancer proliferation, migration and stemness

JournalBmc Cancer

ApplicationWB

IF4.43

SpeciesHuman

PMID26498753
Targeted deletion of miR‐139‐5p activates MAPK, NF‐κB and STAT3 signaling and promotes intestinal inflammation and colorectal cancer

JournalFEBS Journal

ApplicationWB

IF4.392

SpeciesMouse

PMID26859226
Let‐7f Inhibits Glioma Cell Proliferation, Migration, and Invasion by Targeting Periostin

JournalJournal Of Cellular Biochemistry

ApplicationWB

IF4.237

SpeciesHuman

PMID25735962
Suppression of RAD21 Induces Senescence of MDA‐MB‐231 Human Breast Cancer Cells Through RB1 Pathway Activation Via c‐Myc Downregulation

JournalJournal Of Cellular Biochemistry

ApplicationWB

IF4.237

SpeciesHuman

PMID
Water Stress Proteins from Nostoc commune Vauch. Exhibit Anti-Colon Cancer Activities in Vitro and in Vivo

JournalJournal Of Agricultural And Food Chemistry

ApplicationWB

IF4.192

SpeciesHuman

PMID25524246