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HSP90α polyclonal antibody

货号: BS6461

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS6461

Product Name :HSP90α polyclonal antibody

Swiss-Prot :P07900

Host :Rabbit

Reactivity :Human,Mouse,Rat,Monkey

Applications :WB

Application_all :WB 1:500 - 1:2000

Background :Hsp90 is part of the cells powerful network of chaperones to fight the deleterious consequences of protein unfolding caused by nonphysiological conditions. However, in the absence of stress, Hsp90 is a necessary component of fundamental cellular processes such as hormone signaling and cell cycle control. In this context several key regulatory proteins such as steriod receptors, cell cycle kinases involved in signal transduction and p53 have been identified as substrates of Hsp90.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :HSP90α polyclonal antibody detects endogenous levels of HSP90α protein.

BiowMW :~ 101 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Nuclear Receptor Signaling,Regulation of Actin Dynamics,

Alternative Name :Heat shock protein HSP 90-alpha; Heat shock 86 kDa; HSP 86; HSP86; Lipopolysaccharide-associated protein 2; LAP-2; LPS-associated protein 2; Renal carcinoma antigen NY-REN-38; HSP90AA1; HSP90A; HSPC1; HSPCA

Immunogen :Recombinant full length Human HSP90α.

Conjugate :Unconjugated

Modification :Unmodification

WesternBlot (WB) analysis of HSP90α polyclonal antibody

Microvesicle‐Shuttled miR‐130b Reduces Fat Deposition in Recipient Primary Cultured Porcine Adipocytes by Inhibiting PPAR‐γ Expression

JournalJournal Of Cellular Physiology

ApplicationWB

IF5.546

SpeciesPig

PMID24311275
A selenosemicarbazone complex with copper efficiently down-regulates the 90-kDa heat shock protein HSP90AA1 and its client proteins in cancer cells

JournalBmc Cancer

ApplicationWB

IF3.15

SpeciesHuman

PMID25167922
Cell membrane gp96 facilitates HER2 dimerization and serves as a novel target in breast cancer

JournalInternational Journal Of Cancer

ApplicationWB

IF5.145

SpeciesHuman

PMID25546612