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IL-6 polyclonal antibody（KU）

货号: BS6419

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS6419

Product Name :IL-6 polyclonal antibody（KU）

Swiss-Prot :P05231

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:2000 IHC: 1:50~1:200

Background :Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the brea own of fats and to improve insulin resistance.Genetic variations in IL6 are associated with susceptibility to rheumatoid arthritis systemic juvenile. An inflammatory articular disorder with systemic-onset beginning before the age of 16. It represents a subgroup of juvenile arthritis associated with severe extraarticular features and occasionally fatal complications. During active phases of the disorder, patients display a typical daily spiking fever, an evanescent macular rash, lymphadenopathy, hepatosplenomegaly, serositis, myalgia and arthritis.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IL-6 polyclonal antibody detects endogenous levels of IL-6 protein.

BiowMW :~ 23 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Interleukin BSF 2; B cell differentiation factor; B cell stimulatory factor 2; B-cell stimulatory factor 2; BSF 2; BSF-2; BSF2; CDF; CTL differentiation factor; Cytotoxic T cell differentiation factor; Hepatocyte stimulating factor; HGF; HPGF; HSF; Hybridoma growth factor; Hybridoma growth factor Interferon beta-2; Hybridoma plasmacytoma growth factor; IFN-beta-2; IFNB2; IL 6; IL-6; IL6; IL6 protein; IL6; Interferon beta 2; Interferon beta-2; Interleukin 6 (interf

Immunogen :Recombinant full length Human IL-6.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of IL-6 polyclonal antibody at 1:500 dilution Lane1:HCC827 whole cell lysate(40ug) Lane2:PC3 whole cell lysate(40ug

Immunohistochemistry (IHC) analysis of IL-6 pAb in paraffin-embedded Rat Lung tissue.

Specific α7 nicotinic acetylcholine receptor agonist ameliorates isoproterenol‐induced cardiac remodelling in mice through TGF‐β1/Smad3 pathway

JournalClinical And Experimental Pharmacology And Physiology

ApplicationWB

IF2.456

SpeciesMouse

PMID28732106
Evolution of Coronary Flow in an Experimental Slow Flow Model in Swines: Angiographic and Pathological Insights

JournalBiomed Research International

ApplicationWB

IF2.197

SpeciesPig

PMID26539516
Bofutsushosan ameliorates obesity in mice through modulating PGC-1α expression in brown adipose tissues and inhibiting inflammation in white adipose tissues

JournalChinese Journal of Natural Medicines

ApplicationIHC

IF2.014

SpeciesMouse

PMID
Interleukin-6 downregulated vascular smooth muscle cell contractile proteins via ATG4B-mediated autophagy in thoracic aortic dissection

JournalHeart And Vessels

ApplicationIHC

IF1.62

SpeciesHuman

PMID28965202
ING5 knockdown enhances migration and invasion of lung cancer cells by inducing EMT via EGFR/PI3K/Akt and IL-6/STAT3 signaling pathways

JournalOncotarget

ApplicationWB

IF0

SpeciesHuman

PMID28903339