Product Name :Histone H3 (Mono-Methyl K37) polyclonal antibody
Swiss-Prot :P68431; Q71DI3; P84243; Q6NXT2
Reactivity :Human,Mouse,Rat
Application_all :WB: 1:500~1:1000
Background :Chromatin is the arrangement of DNA and proteins in which chromosomes are formed. Correspondingly, chromatin is formed from nucleosomes, which are comprised of a set of four histone proteins (H2A, H2B, H3, H4) wrapped with DNA. Chromatin is a very dynamic structure in which numerous post-translational modifications work together to activate or repress the availability of DNA to be copied, transcribed, or repaired. These marks decide which DNA will be open and commonly active (euchromatin) or tightly wound to prevent access and activation (heterochromatin). Common histone modifications include methylation of lysine and arginine, acetylation of lysine, phosphorylation of threonine and serine, and sumoylation, biotinylation, and ubiquitylation of lysine.
Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 96% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Histone H3 (Mono-Methyl K37) polyclonal antibody detects endogenous levels of Histone H3 protein only when Methyl at Lys37.
Note :For research use only, not for use in diagnostic procedure.
Pathway :Histone Lysine Methylation Pathway,Examples of Crosstalk Between Post-translational Modifications,DNA Methylation,
Alternative Name :Histone H3.1; Histone H3A; H3FA; Histone H3B; H3FL; Histone H3C; H3FC; Histone H3D; H3FB; Histone H3E; H3FD; Histone H3F; H3FI; Histone H3G; H3FH; Histone H3H; H3FK; Histone H3I; H3FF; Histone H3J; H3FJ; Histone H3.2; Histone H3/m; Histone H3/o; HIST2H3A; HIST2H3C; H3F2; H3FM; HIST2H3
Immunogen :Synthetic peptide derived from human Histone H3 around the Mono-Methyl at K37.
