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Ubiquitin polyclonal antibody

货号: BS62242

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS62242

Product Name :Ubiquitin polyclonal antibody

Swiss-Prot :P0CG47/P0CG48/P62979/P62987

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB:1:500~1:1000

Background :Ubiquitin (Ub) is among the most phylogenetically conserved proteins known. The primary function of ubiquitin is to clear abnormal, foreign and improperly folded proteins by targeting them for degradation by the 26S proteosome. This small, 76 amino acid protein can be covalently attached to cellular proteins via an isopeptide linkage between the carboxy terminal group of ubiquitin and lysine amino groups on the acceptor protein. For proteolysis to occur, ubiquitin oligomers must be assembled. Ubiquitin chains on proteolytic substrates are commonly found to have an isopeptide bridge between Lysine 48 of one ubiquitin molecule and the carboxy-terminus of a neighboring ubiquitin molecule.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Ubiquitin polyclonal antibody detects endogenous levels of Ubiquitin protein.

BiowMW :~ 25 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Ubiquitin Proteasome,Autophagy Signaling,

Alternative Name :Polyubiquitin-B; Ubiquitin; UBB; Polyubiquitin-C; UBC; RPS27A; UBA80; UBCEP1; CEP52; UBA52; UBCEP2

Immunogen :Synthetic peptide, corresponding to Human Ubiquitin.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of Ubiquitin polyclonal antibody at 1:500 dilution LaneA:Hela whole cell lysate LaneB:LO2 whole cell lysate LaneC:PC3 whole cell lysate

Targeting HMGB2 acts as dual immunomodulator by bolstering CD8+ T cell function and inhibiting tumor growth in hepatocellular carcinoma

JournalScience Advances

ApplicationWB

IF11.7

SpeciesMouse

PMID40315321