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GIMAP4 polyclonal antibody

货号: BS61682

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS61682

Product Name :GIMAP4 polyclonal antibody

Swiss-Prot :Q9NUV9

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :The GTPase of the immunity-associated protein (GIMAP) family of proteins include seven members that are expressed by genes residing on human chromosome 7. GIMAP proteins have been implicated in the regulation of lymphomyeloid cell survival. GIMAP4 (GTPase IMAP family member 4), also known as IMAP4 (immunity-associated protein 4) and IAN1 (immunityassociated nucleotide 1 protein), is a 329 amino acid protein that contains 5 motifs that are conserved in GTP-binding proteins and a C-terminal coiledcoiled region that may be responsible for protein-protein interactions. GIMAP4 exhibits intrinsic GTPase activity that is highly dependent on magnesium concentration to bind GDP. Showing differential regulation during T-helper cell differentiation, GIMAP4 appears to regulate the apoptosis of T cells. GIMAP4 is specifically expressed in resting T and B lymphocytes and its protein expression is appreciably decreased upon T or B lymphocyte activation.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :GIMAP4 polyclonal antibody detects endogenous levels of GIMAP4 protein.

BiowMW :~ 37 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :GTPase IMAP family member 4; Immunity-associated nucleotide 1 protein; IAN-1; hIAN1; Immunity-associated protein 4; GIMAP4; IMAP4; IAN1; MSTP062

Immunogen :Synthetic peptide, corresponding Human GIMAP4.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of GIMAP4 polyclonal antibody at 1:500 dilution Lane1:CT26 whole cell lysate(40ug) Lane2:HCT116 whole cell lysate(40ug) Lane3:A2780 whole cell lysate(40ug) Lane4:The Spleen tissue lysate of Mouse(40ug) Lane5:The Spleen tissue lysate of Rat(40ug)